The possibility that either dental fluorosis (Chapter 4) or the
delayed tooth eruption noted with high fluoride intake (Chapter 4; see also Short 1944) may be attributable at least in part to an effect of fluoride on thyroid function has not been studied. (NRC
2006, page 198)
This statement is entirely untrue. This issue has been studied for many decades
since the early 1900ís (Schuld, 2005; McKay, 1918; Wilson & De Eds, 1940; Steyn, 1964; etc.). The Review itself cites numerous studies which have found clear evidence that fluoride and thyroid
hormones have "mutually interacting effects" on 'dental fluorosis' (i.e Zhao et al, 1998; Yang et al, 1994; Lin et al, 1991).
See also comment: Delayed Eruption
Lin Fa-Fu, Aihaiti, Zhao Hong-Xin, Lin Jin, Jiang Ji-Yong, Maimaiti, and Aiken The
Relationship of a Low-Iodine and High-Fluoride Environment to Subclinical Cretinism in Xinjiang. Endem Dis Bull 1991;(6)62-68
McKay, FS. Progress of the year in the investigation of mottled enamel with special reference to its association with artesian water. J Natl Dental Assn 1918;5:721
Schuld A. Is Dental Fluorosis Caused By Thyroid Hormone Disturbances?
Fluoride 2005; 38(2)91-94
Steyn DG. Once More - Fluoridation. Review. University of Pretoria NUWE REEKS No.24 (1964)
Wilson RH, DeEds F.The Synergistic Action Of Thyroid On Fluoride
Toxicity. Endocrinology 1940;26:851
Yang Y, Wang X, Guo X. Effects of high iodine and high fluorine on children's
intelligence and the metabolism of iodine and fluorine.
Chinese Journal of Epidemiology 15(5):296-8 (1994)
Zhao WY. A preliminary study of the interaction of iodide and fluoride in experimental
iodide-goiter and fluorosis. Chinese Preventive Medicine 1988;22:146-148
Zhao W, Zhu H, Yu Z, Aoki K, Misumi J, Zhang X.Long-term Effects of Various Iodine and
Fluorine Doses on the Thyroid and Fluorosis in Mice.
Endocr Regul 1998;32(2):63-70